Development of novel 2-aminoalkyl-6-(2-hydroxyphenyl)pyridazin-3(2H)-one derivatives as balanced multifunctional agents against Alzheimer's disease

已完结 10 由饼干发布于 2025/1/20 10:15:14

DOI:10.1016/j.ejmech.2021.114098
作者：Yichun Shi , Heng Zhang , Qing Song , Guangjun Yu , Zhuoling Liu , Feng Zhong , Zhenghuai Tan , Xiuxiu Liu , Yong Deng
文献类型：期刊论文
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Elsevier

Abstract：Based on multitarget-directed ligands approach, through two rounds of screening, a series of 2-aminoalkyl-6-(2-hydroxyphenyl)pyridazin-3(2H)-one derivatives were designed, synthesized and ev

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