Process Research for ZG1077, a KRAS G12C Inhibitor

已完结 10 由 kalaka 发布于 2025/1/17 17:06:06

DOI:10.1021/acs.oprd.2c00284
文献类型：期刊论文
补充材料：只需要正文
文献链接：https://doi.org/10.1021/acs.oprd.2c00284

American Chemical Society (ACS)

Abstract：A novel, efficient, and robust synthetic route to ZG1077 with an atropisomer structure for KRAS G12C inhibitors was designed. The critical process parameters were optimized and established t

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