Synthesis of gem-Difluoroalkenes via Ni-Catalyzed Three-Component Defluorinative Reductive Cross-Coupling of Organohalides, Alkenes and Trifluoromethyl Alkenes

已完结 10 由李生发布于 2025/2/4 12:02:41

DOI:10.1002/cjoc.202200277
作者：Teng Ma,?Xiao Li,?Yuanyuan Ping,?Wangqing Kong
文献类型：期刊论文
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Wiley

Abstract： gem-Difluoroalkenes are considered ideal isosteres for metabolically susceptible carbonyl groups in modern drug discovery and medicinal chemistry. In addition, gem-difluo

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