HIF1α Counteracts TGFβ1-Driven TSP1 Expression in Endothelial Cells to Stimulate Angiogenesis in the Hypoxic Tumor Microenvironment.

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DOI:10.1158/0008-5472.CAN-24-2324
作者：Yu-Wei Luo,?Yang Fang,?Hui-Xian Zeng,?Yu-Chen Ji,?Meng-Zhi Wu,?Hui Li,?Jie-Ying Chen,?Li-Min Zheng,?Jian-Hong Fang,?Shi-Mei Zhuang
文献类型：期刊论文
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American Association for Cancer Research (AACR)

Abstract：Emerging evidence suggests that TGFβ1 can inhibit angiogenesis, contradicting the coexistence of active angiogenesis and high abundance of TGFβ1 in the tumor microenvironment. Here, we inves

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