Multiplex genome editing eliminates lactate production without impacting growth rate in mammalian cells

已完结 10 由 woaidaan 发布于 2025/2/6 13:31:15

DOI:10.1038/s42255-024-01193-7
作者：Hooman Hefzi,?Iván Martínez-Monge,?Igor Marin de Mas,?Nicholas Luke Cowie,?Alejandro Gomez Toledo,?Soo Min Noh,?Karen Julie la Cour Karottki,?Marianne Decker,?Johnny Arnsdorf,?Jose Manuel Camacho-Za
文献类型：期刊论文
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Nature

Abstract：The Warburg effect, which describes the fermentation of glucose to lactate even in the presence of oxygen, is ubiquitous in proliferative mammalian cells, including cancer cells, but poses c

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