Lipid nanoparticle-mediated mRNA delivery to CD34+ cells in rhesus monkeys

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DOI:10.1038/s41587-024-02470-2
作者：Hyejin Kim, Ryan Zenhausern, Kara Gentry, Liming Lian, Sebastian G. Huayamares, Afsane Radmand, David Loughrey, Ananda R. Podilapu, Marine Z. C. Hatit, Huanzhen Ni, Andrea Li, Aram Shajii, Hannah E. P
文献类型：期刊论文
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Nature

Abstract：Transplantation of ex vivo engineered hematopoietic stem cells (HSCs) can lead to robust clinical responses but carries risks of adverse events from bone marrow mobilization, chemotherapy co

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