Carnosic Acid: A Novel Selective Inhibitor of ERAP1 by Direct Binding and Its Modulation of Antigen Processing and Presentation

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DOI:10.1021/acs.jafc.4c0095710.1021/acs.jafc.4c00957
文献类型：期刊论文
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文献链接：https://doi.org/10.1021/acs.jafc.4c0095710.1021/acs.jafc.4c00957

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Abstract：ERAP1 is an emerging target for a large subclass of severe autoimmune diseases known as “MHC-I-opathy”, together with tumor immunity. Nevertheless, effective inhibitors targeting ERAP1 remai

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