Hapalindole Q suppresses autophagosome?lysosome fusion by promoting YAP1 degradation via chaperon-mediated autophagy

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DOI:10.1073/pnas.2400809121
作者：Yali Wu, Shaonan Wang, Zhicong Guo, Min Sun, Zhen Xu, Yu Du, Fahui Zhu, Yajuan Su, Zhou Xu, Yi Xu, Xu Gong, Ruan Fang, Jiaojiao Hu, Yan Peng, Zhaowen Ding, Cong Liu, Ang Li, Weiwei He
文献类型：期刊论文
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Proceedings of the National Academy of Sciences of the United States of America (PNAS)

Abstract：Autophagy is a conserved catabolic process crucial for maintaining cellular homeostasis and has emerged as a promising therapeutic target for many diseases. Mechanistically novel small-molec

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