Direct Synthesis of Aryloxy Phosphonamidate Nucleotide Prodrugs Using the Cross Metathesis Assisted by Ultrasonic Irradiation

已完结 10 由 Tony 发布于 2024/12/25 21:31:55

DOI:10.1021/acs.orglett.4c00094
作者：Se Myeong Choi,?Ye Eun Nam,?Yeon Jin An,?Eun Rang Choi,?Hyejin Park,?Raymond F. Schinazi and Jong Hyun Cho*,?
文献类型：期刊论文
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American Chemical Society (ACS)

Abstract：A direct synthetic strategy of aryloxy phosphonamidate nucleotide prodrugs (A, G, C, and U) was developed with the CM reaction assisted by ultrasonic irradiation and partitioned addition of

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