The D2D3 form of uPAR acts as an immunotoxin and may cause diabetes and kidney disease

已完结 10 由 Holly 发布于 2024/12/30 16:11:23

DOI:10.1126/scitranslmed.abq6492
作者：Ke?Zhu,?Kamalika?Mukherjee,?Changli?Wei,?Salim S.?Hayek,?Agnieszka?Collins,?Changkyu?Gu,?Kristin?Corapi,?Mehmet M.?Altintas,?Yong?Wang,?Sushrut S.?Waikar,?Antonio C.?Bianco,?Alexander?Koch,?Frank?Tack
文献类型：期刊论文
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American Association for the Advancement of Science (AAAS)

Abstract：Soluble urokinase plasminogen activator receptor (suPAR) is a risk factor for kidney diseases. In addition to suPAR, proteolysis of membrane-bound uPAR results in circulating D1 and D2D3 pro

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