High efficiency biosynthesis of 1α,25-Dihydroxyvitamin D3 via engineered dihydroxylase and deep eutectic solvent based resting cell bioprocess

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DOI:10.1016/j.biortech.2026.134526
作者：Fan He , Qiaoqiao Ma , Huahua Zhang , Junheng Gou , Qingbo Deng , Jinsong Gong , Jinsong Shi , Zhenghong Xu , Hui Li
文献类型：期刊论文
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Elsevier

Abstract：1α,25-dihydroxyvitamin D3 (1α,25(OH)2VD3), the biologically active form of Vitamin D3 (VD3), plays a crucial role in a wide range of physiological processes. However, the efficient biosynthe

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