Insulin-Degrading Enzyme Efficiently Degrades polyQ Peptides but not Expanded polyQ Huntingtin Fragments.

已完结 10 由 xxx 发布于 2025/3/10 13:53:29

DOI:10.3233/jhd-230583
作者：Karlijne W Geijtenbeek, Angela Santiago Aranda, Alicia Sanz Sanz, Jolien Janzen, Aleksandra E. Bury, Suzan Kors, Nur Al Amery, Nina C.M. Schmitz, Eric Reits, Sabine Schipper-Krom
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Abstract：Background Huntington's disease is an inheritable autosomal dominant disorder caused by an expanded CAG trinucleotide repeat within the Huntingtin gene, leading to a polyglutamine (polyQ) ex

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