Bicyclic Isosteres of Pyridine/Piperidine: From Synthesis to Applications

已完结 10 由小新发布于 2026/7/17 16:06:44

DOI:10.1002/anie.202517814
作者：Oleksandr Stashkevych,?Volodymyr Kokhalskyi,?Yevhenii Mynak,?Vadym Levterov,?Oleh Shablykin,?Iryna Pishel,?Pavel K. Mykhailiuk
文献类型：期刊论文
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Wiley

Abstract：2-Azabicyclo[2.2.2]octanes have been designed, synthesized, and validated biologically as isosteres of piperidine/pyridine. The key reaction step was the cyclization of cyclic alkenyl amines

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