Chimeric Biocatalyst Combining Peptidic and Nucleic Acid Components Overcomes the Performance and Limitations of the Native Horseradish Peroxidase

已完结 10 由 zcc 发布于 2025/3/19 17:07:04

DOI:10.1021/jacs.2c11318
作者：Xiaobo Zhang,?Dehui Qiu,?Jielin Chen,?Yue Zhang,?Jiawei Wang,?Desheng Chen,?Yuan Liu,?Mingpan Cheng,?David Monchaud,?Jean-Louis Mergny,?Huangxian Ju and Jun Zhou*,?
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Abstract：Chimeric peptide-DNAzyme (CPDzyme) is a novel artificial peroxidase that relies on the covalent assembly of DNA, peptides, and an enzyme cofactor in a single scaffold. An accurate control of

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