Optimization of Single Relaxin B-Chain Peptide Leads to the Identification of R2R01, a Potent, Long-Acting RXFP1 Agonist for Cardiovascular and Renal Diseases.

已完结 10 由 KK 发布于 2025/2/10 10:38:17

DOI:10.1021/acs.jmedchem.4c03085
作者：Sergio Mallart,?Raffaele Ingenito,?Paola Magotti,?Alberto Bresciani,?Annalise Di Marco,?Simone Esposito,?Edith Monteagudo,?Fulvia Caretti,?Laura Orsatti,?Alessia Santoprete,?Daniela Roversi,?Federica
文献类型：期刊论文
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American Chemical Society (ACS)

Abstract：Peptide 1, a C18 fatty acid-modified single-chain relaxin analogue, was recently identified as a potent, selective, and long-lasting relaxin family peptide receptor 1 (RXFP1) agonist. Furthe

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