Single-cell multiomics of neuron activation reveals context-specific genetics of brain disorders

已完结 10 由 OM 发布于 2026/7/17 11:23:02

DOI:10.1126/science.adw3949
作者：Lifan Liang,?Siwei Zhang,?Zicheng Wang,?Hanwen Zhang,?Chuxuan Li,?Christina Thapa,?Emily K. Oh,?David Sirkin,?Xiaotong Sun,?Alexandra Barishman,?Ada McCarroll,?Alexandra C. Duhe,?Sheng Qian,?Xiaoyuan
文献类型：期刊论文
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American Association for the Advancement of Science (AAAS)

Abstract：Most causal variants for neuropsychiatric disorders (NPD) remain unknown. A major hurdle is that disease variants may act in specific contexts, such as during neuronal activation, which is d

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