Mechanism-Guided Computational Design Drives meso-Diaminopimelate Dehydrogenase to Efficient Synthesis of Aromatic d-amino Acids

已完结 10 由郑棚发布于 2025/2/13 15:30:25

DOI:10.1021/acssynbio.4c00176
作者：Tianfu Wu 1 2, Yihan Chen 2, Wanqing Wei 1, Wei Song 2, Jing Wu 2, Jian Wen 2, Guipeng Hu 2, Xiaomin Li 1, Cong Gao 1, Xiulai Chen 1, Liming Liu 1
文献类型：期刊论文
补充材料：只需要正文
文献链接：https://doi.org/10.1021/acssynbio.4c00176

American Chemical Society (ACS)

Abstract：Aromatic d-amino acids (d-AAs) play a pivotal role as important chiral building blocks and key intermediates in fine chemical and drug synthesis. Meso-diaminopimelate dehydrogenase (DAPDH) s

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