Small molecule FGF23 inhibitors increase serum phosphate and improve skeletal abnormalities in Hyp mice

已完结 10 由肝论文的秃头小白发布于 2025/2/18 16:51:00

DOI:10.1101/2020.08.04.236877
作者：Zhousheng Xiao,?Jiawang Liu,?Shih-Hsien Liu,?Siyi Liu,?Loukas Petridis,?Loukas Petridis,?C. Cai,?Li-zhen Cao,?Guangwei Wang,?A. L. Chin,?Jacob W. Cleveland,?Munachi O. Ikedionwu,?J. Carrick,?Jeremy C.
文献类型：期刊论文
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Cold Spring Harbor Laboratory (CSH)

Abstract：Fibroblast growth factor 23 (FGF23) is a bone-derived hormone that binds to binary FGFR/α-Klotho receptor complexes in the kidney tubules to inhibit phosphate reabsorption and 1,25(OH)2D pro

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