Racemic Synthesis of a Key 1,4-Dihydro-2H-spiro[isoquinoline-3,4′-piperidin]-3′-ol Building Block

已完结 10 由小太阳发布于 2025/2/26 10:02:54

DOI:10.1021/acs.oprd.2c00121
文献类型：期刊论文
补充材料：只需要正文
文献链接：https://doi.org/10.1021/acs.oprd.2c00121

American Chemical Society (ACS)

Abstract：The synthesis of a key spiroamine building block for a medicinal chemistry program is described. Key innovations were a regioselective epoxide ring opening and a late-stage Pictet–Spengler r

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