The Nonclinical Safety Assessment of a Novel Anti-CEACAM5 Antibody Exatecan Conjugate Predicts a Low Risk for Interstitial Lung Disease (ILD) in Patients-The Putative Mechanism Behind ILD.

已完结 10 由 karry 发布于 2025/3/3 13:10:39

DOI:10.1177/10915818241306039
作者：Willem N Sloot,?Elisa Bertotti,?Manuela Onidi,?Andrea Paoletti,?Ilse De Salve,?Patrizia Tavano,?Enrico Vigna,?Gundi Mueller
文献类型：期刊论文
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Abstract：The therapeutic window of antibody drug-conjugates (ADC) remains challenging due to safety issues such as interstitial lung disease (ILD) observed with specific deruxtecan-based ADCs. To avo

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