Intein-mediated temperature control for complete biosynthesis of sanguinarine and its halogenated derivatives in yeast

已完结 10 由立秋发布于 2024/9/13 15:25:39

DOI:10.1038/s41467-024-49554-w
作者：Yuanwei Gou, Dongfang Li, Minghui Zhao, Mengxin Li, Jiaojiao Zhang, Yilian Zhou, Feng Xiao, Gaofei Liu, Haote Ding, Chenfan Sun, Cuifang Ye, Chang Dong, Jucan Gao, Di Gao, Zehua Bao, Lei Huang, Zhinan
文献类型：期刊论文
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Nature

Abstract：While sanguinarine has gained recognition for antimicrobial and antineoplastic activities, its complex conjugated structure and low abundance in plants impede broad applications. Here, we de

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