Ammonia-induced lysosomal and mitochondrial damage causes cell death of effector CD8+ T cells

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DOI:10.1038/s41556-024-01503-x
作者：Huafeng Zhang, Jincheng Liu, Wu Yuan, Qian Zhang, Xiao Luo, Yonggang Li, Yue’e Peng, Jingyu Feng, Xiaoyu Liu, Jie Chen, Yabo Zhou, Jiadi Lv, Nannan Zhou, Jingwei Ma, Ke Tang, Bo Huang
文献类型：期刊论文
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Nature

Abstract：Ammonia is thought to be a cytotoxin and its increase in the blood impairs cell function. However, whether and how this toxin triggers cell death under pathophysiological conditions remains

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