Enhancing the apo protein tyrosine phosphatase non-receptor type 2 crystal soaking strategy through inhibitor-accessible binding sites

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DOI:10.1107/S2053230X24007866
作者：Stephanie M. Bester, Rebecca Linwood, Ryoko Kataoka, Wen-I Wu, Tung-Chung Mou
文献类型：期刊论文
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International Union of Crystallography (IUCr)

Abstract：Protein tyrosine phosphatase non-receptor type 2 (PTPN2) has recently been recognized as a promising target for cancer immunotherapy. Despite extensive structural and functional studies of o

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