Interleukin-2-Inducible T-Cell Kinase (ITK) Inhibitors for the Treatment of T-Cell Lymphoproliferative Disorders

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DOI:10.1182/blood-2018-99-110554
作者：J. Reneau,?S. Hwang,?C. Murga-Zamalloa,?J. Buggy,?J. Janc,?R. Wilcox
文献类型：期刊论文
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Abstract： Introduction: We previously demonstrated that engagement of the T-cell receptor (TCR) in malignant T-cells leads to ITK-dependent activation of the transcription factors NF-κB and GATA3, t

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