Design, synthesis, and biological evaluation of 1,6-naphthyridine-2-one derivatives as novel FGFR4 inhibitors for the treatment of colorectal cancer

已完结 10 由陌上花开发布于 2024/7/26 13:06:35

DOI:10.1016/j.ejmech.2023.115703
作者：Bo Fang , Yinshuang Lai , Hao Yan , Yue Ma , Zefeng Ni , Qianqian Zhu , Jianxia Zhang , Yanfei Ye , Mengying Wang , Peipei Wang , Yan Wang , Shuyuan Zhang , Min Hui , Dalong Wang , Yunjie Zhao , Xiaokun Li , Kun Wang , Zhiguo Liu
文献类型：期刊论文
补充材料：只需要正文

Elsevier

Abstract：Aberrant FGFR4 signaling has been implicated in the development of several cancers, making FGFR4 a promising target for cancer therapy. Several FGFR4-selective inhibitors have been developed

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