Preclinical proof of principle for orally delivered Th17 antagonist miniproteins

已完结 10 由 phyjun 发布于 2024/7/23 0:25:15

DOI:10.1016/j.cell.2024.05.052
作者：Stephanie Berger, Franziska Seeger, Ta-Yi Yu, Merve Aydin, Huilin Yang, Daniel Rosenblum, Laure Guenin-Macé, Caleb Glassman, Lauren Arguinchona, Catherine Sniezek, Alyssa Blackstone, Lauren Carter, Rashmi Ravichandran, Maggie Ahlrichs, Michael Murphy, Ingrid Swanson Pultz, Alex Kang, Asim K. Bera, Lance Stewart, K. Christopher Garcia, David Baker
文献类型：期刊论文
补充材料：只需要正文

Elsevier

Abstract：Interleukin (IL)-23 and IL-17 are well-validated therapeutic targets in autoinflammatory diseases. Antibodies targeting IL-23 and IL-17 have shown clinical efficacy but are limited by high c

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