Attenuating ribosome load improves protein output from mRNA by limiting translation-dependent mRNA decay

已完结 10 由钱钱发布于 2024/8/1 21:53:11

DOI:10.1016/j.celrep.2024.114098
文献类型：期刊论文
补充材料：只需要正文
文献链接：https://doi.org/10.1016/j.celrep.2024.114098

Elsevier

Abstract：Developing an effective mRNA therapeutic often requires maximizing protein output per delivered mRNA molecule. We previously found that coding sequence (CDS) design can substantially affect

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