Identification of the anti-fungal drug fenticonazole nitrate as a novel PPARγ-modulating ligand with good therapeutic index: Structure-based screening and biological validation

已完结 10 由纯情无敌霹雳牛马发布于 2024/8/3 23:43:57

DOI:10.1016/j.phrs.2021.105860
作者：Lei Ma , Yuling Lian , Junyuan Tang , Fangyuan Chen, Hui Gao, Zhi Zhou, Ning Hou, Wei Yi
文献类型：期刊论文
补充材料：只需要正文
文献链接：https://doi.org/10.1016/j.phrs.2021.105860

Elsevier

Abstract：In this study, SB-VHTS of the old drug library was conducted to seek for novel PPARγ ligand. In the end, an antifungal drug, FN, was identified in vitro and in vivo as a new and potent PPARγ

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