Design, Synthesis, and Structure–Activity Relationship Studies of Bisamide Derivatives of Amphotericin B with Potent Efficacy and Low Toxicity

已完结 10 由杨小木发布于 2024/8/10 22:46:10

DOI:10.1021/acs.jmedchem.1c02227
作者：Huijun Ma, Anran Qian, Yazhou Zheng, Xin Meng, Ting Wang, Yinyong Zhang, Lulu Sun, Feng Zou, Bomei Zhao, Shuhua Zhang, Dan Zhang* and Yushe Yang*, 
文献类型：期刊论文
补充材料：只需要正文

American Chemical Society (ACS)

Abstract：Amphotericin B (AMB, 1) is the most powerful antibiotic in treating potentially life-threatening invasive fungal infections (IFIs), though severe toxicity derived from self-aggregation great

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