Substituting Poly(ethylene glycol) Lipids with Poly(2-ethyl-2-oxazoline) Lipids Improves Lipid Nanoparticle Repeat Dosing

已完结 10 由 1236544 发布于 2024/8/8 9:05:03

DOI:10.1002/adhm.202304033
作者：Alejandro J. Da Silva Sanchez, David Loughrey, Elisa Schrader Echeverri, Sebastian G. Huayamares, Afsane Radmand, Kalina Paunovska, Marine Hatit, Karen E. Tiegreen, Philip J. Santangelo, James E. Dahlman
文献类型：期刊论文
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Wiley

Abstract：Poly(ethylene glycol) (PEG)–lipids are used in Food-and-Drug-Administration-approved lipid nanoparticle (LNP)–RNA drugs, which are safe and effective. However, it is reported that PEG–lipids

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