Deep-learning-based design of synthetic orthologs of SH3 signaling domains.

已完结 10 由 phyjun 发布于 2024/8/12 23:04:37

DOI:10.1016/j.cels.2024.07.005
作者：Xinran Lian, Nikša Praljak, Subu K Subramanian, Sarah Wasinger, Rama Ranganathan, Andrew L Ferguson
文献类型：期刊论文
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Elsevier

Abstract：Evolution-based deep generative models represent an exciting direction in understanding and designing proteins. An open question is whether such models can learn specialized functional const

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