PD-1 inhibits T cell actin remodeling at the immunological synapse independently of its signaling motifs

已完结 10 由 TK 发布于 2024/11/11 17:04:16

DOI:10.1126/scisignal.adh2456
作者：Noémie Paillon,&nbsp;Violette Mouro,&nbsp;Stéphanie Dogniaux,&nbsp;Mathieu Maurin,&nbsp;Juan-José Saez Pons,&nbsp;Hermine Ferran,&nbsp;Laurence
文献类型：期刊论文
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American Association for the Advancement of Science (AAAS)

Abstract：Engagement of the receptor programmed cell death molecule 1 (PD-1) by its ligands PD-L1 and PD-L2 inhibits T cell–mediated immune responses. Blocking such signaling provides the clinical eff

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