Development of a Concise Process for the Synthesis of the Azaindazole Core of the CD73 Inhibitor AB680

已完结 10 由胖子发布于 2024/11/13 19:04:44

DOI:10.1021/acs.oprd.3c00056
作者：Xiaopeng Yin,?Zhiguo Jake Song,?Jaroslaw Kalisiak,?Jonathan C. Tripp,?Xiao Lei,?Hongfeng Li and Aimin Zhang*,?
文献类型：期刊论文
补充材料：只需要正文

American Chemical Society (ACS)

Abstract：AB680 is a highly potent small-molecule CD73 inhibitor discovered and developed by Arcus Biosciences, currently in clinical trials for the treatment of pancreatic cancer. Herein, we report a

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