Practical and Efficient Approach to Scalable Synthesis of Rucaparib

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DOI:10.1021/acs.oprd.4c00366
作者：Jinjae Park, Cheol-Hong Cheon
文献类型：期刊论文
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American Chemical Society (ACS)

Abstract：A scalable synthesis of rucaparib was developed from methyl 5-fluoro-2-methyl-3-nitrobenzoate and 4-cyanobenzaldehyde. Methyl 5-fluoro-2-methyl-3-nitrobenzoate was converted into a 2-aminoci

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