Multiscale drug screening for cardiac fibrosis identifies MD2 as a therapeutic target

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DOI:10.1016/j.cell.2024.09.034
作者：Hao Zhang, Phung N. Thai, Rabindra V. Shivnaraine, Lu Ren, Xuekun Wu, Dirk H. Siepe, Yu Liu, Chengyi Tu, Hye Sook Shin, Arianne Caudal, Souhrid Mukherjee, Jeremy Leitz, Wilson Tan Lek Wen, Wenqiang Li
文献类型：期刊论文
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Elsevier

Abstract：Cardiac fibrosis impairs cardiac function, but no effective clinical therapies exist. To address this unmet need, we employed a high-throughput screening for antifibrotic compounds using hum

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