A system of paired polyether epoxide hydrolases enables a mouldable enzyme for consecutive ring cyclization cascades.

已取消 10 由十七发布于 2026/4/26 12:15:41

DOI:10.1038/s41557-026-02122-9
作者：Nana Yabuno,Atsushi Minami,Taro Ozaki,Yuki Owada,Kohei Sawada,Ayaka Arai,Shusuke Sato,Aoi Sugiyama,Takashi Tadokoro,Tomoyasu Aizawa,Takuya Dosen,Tomo Nomai,Takanori Matsumaru,Junyang Liu,Tao Ye,Atsuji
文献类型：期刊论文
补充材料：只需要正文
文献链接：https://doi.org/10.1038/s41557-026-02122-9

Nature

Abstract：Ionophore polyethers, a major class of polyketide-derived natural products, are characterized by molecular skeletons featuring arrays of tetrahydrofuran and tetrahydropyran rings. However, t

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