Targeting overexpressed antigens in glioblastoma via CAR T cells with computationally designed high-affinity protein binders

已完结 10 由 phyjun 发布于 2024/11/24 14:57:04

DOI:10.1038/s41551-024-01258-8
作者：Zhen Xia, Qihan Jin, Zhilin Long, Yexuan He, Fuyi Liu, Chengfang Sun, Jinyang Liao, Chun Wang, Chentong Wang, Jian Zheng, Weixi Zhao, Tianxin Zhang, Jeremy N. Rich, Yongdeng Zhang, Longxing Cao, Qi Xi
文献类型：期刊论文
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Nature

Abstract：Chimeric antigen receptor (CAR) T cells targeting receptors on tumour cells have had limited success in patients with glioblastoma. Here we report the development and therapeutic performance

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