Structure-guided discovery of ancestral CRISPR-Cas13 ribonucleases

已完结 10 由 phyjun 发布于 2024/11/23 22:03:21

DOI:10.1126/science.adq0553
作者：Peter H. Yoon, Zeyuan Zhang, Kenneth J. Loi, Benjamin A. Adler, Arushi Lahiri, Kamakshi Vohra, Honglue Shi, Daniel Bellieny Rabelo, Marena Trinidad, Ron S.
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American Association for the Advancement of Science (AAAS)

Abstract：The RNA-guided ribonuclease CRISPR-Cas13 enables adaptive immunity in bacteria and programmable RNA manipulation in heterologous systems. Cas13s share limited sequence similarity, hindering

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