Process Development for the Manufacture of a Topical Pan-Trk Inhibitor Incorporating Decarboxylative sp2–sp3 Cross-Coupling

已完结 10 由小太阳发布于 2024/12/2 14:55:30

DOI:10.1021/acs.oprd.4c00325
文献类型：期刊论文
补充材料：只需要正文
文献链接：https://doi.org/10.1021/acs.oprd.4c00325

American Chemical Society (ACS)

Abstract：The development of a synthetic route toward topical pan-Trk inhibitor 1 is described as an eight-stage synthesis from available starting materials. Process improvements include the developme

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