De novo protein design with a denoising diffusion network independent of pretrained structure prediction models.

已完结 10 由 phyjun 发布于 2024/10/17 12:21:45

DOI:10.1038/s41592-024-02437-w
作者：Yufeng Liu,?Sheng Wang,?Jixin Dong,?Linghui Chen,?Xinyu Wang,?Lei Wang,?Fudong Li,?Chenchen Wang,?Jiahai Zhang,?Yuzhu Wang,?Si Wei,?Quan Chen,?Haiyan Liu
文献类型：期刊论文
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Nature

Abstract：The recent success of RFdiffusion, a method for protein structure design with a denoising diffusion probabilistic model, has relied on fine-tuning the RoseTTAFold structure prediction networ

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