Discovery of Natural Ah Receptor Antagonists from Salvia miltiorrhiza Bunge and Synthesis of Analogs for Tumor Immunotherapy

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DOI:10.1021/acs.jmedchem.3c01740
作者：Zhenyuan Li,?Shuying Li,?Zeyu Xing,?Quanchang Gu,?Rongrong Du,?Jianshuang Jiang,?Xiang Yuan,?Xu Zhang,?Xiaoguang Chen,?Nina Xue*,?Peicheng Zhang*,?Jing Jin* and Yanan Yang*,?
文献类型：期刊论文
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American Chemical Society (ACS)

Abstract：IDO/TDO/Kyn/AhR signaling plays a crucial role in regulating innate and adaptive immunity, and targeting Ah receptor (AhR) inhibition can potentially redirect immune cells toward an antitumo

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