Preclinical proof of principle for orally delivered Th17 antagonist miniproteins

已完结 10 由 Tony 发布于 2024/11/2 16:02:05

DOI:10.1016/j.cell.2024.05.052
作者：Stephanie Berger, Franziska Seeger, Ta-Yi Yu, Merve Aydin, Huilin Yang, Daniel Rosenblum, Laure Guenin-Macé, Caleb Glassman, Lauren Arguinchona, Catherine Sniezek, Alyssa Blackstone, Lauren Carter, R
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Abstract：Interleukin (IL)-23 and IL-17 are well-validated therapeutic targets in autoinflammatory diseases. Antibodies targeting IL-23 and IL-17 have shown clinical efficacy but are limited by high c

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