MEK inhibition overcomes chemoimmunotherapy resistance by inducing CXCL10 in cancer cells.

已完结 10 由 SONGZI 发布于 2024/2/21 18:27:12

DOI:10.1016/j.ccell.2021.12.009
作者：Emeric Limagne, Lisa Nuttin, Marion Thibaudin, Elise Jacquin, Romain Aucagne, Marjorie Bon, Solène Revy, Robby Barnestein, Elise Ballot, Caroline Truntzer, Valentin Derangère, Jean-David Fumet, Charlène Latour, Cédric Rébé, Pierre-Simon Bellaye, Coureche-Guillaume Kaderbhaï, Aodrenn Spill, Bertrand Collin, Mary B Callanan, Aurélie Lagrange, Laure Favier, Bruno Coudert, Laurent Arnould, Sylvain Ladoire, Bertrand Routy, Philippe Joubert, François Ghiringhelli
文献类型：期刊论文
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Elsevier

Abstract：Chemotherapy with anti PD-1/PD-L1 antibodies has become the standard of care for patients with metastatic non-small cell lung cancer (mNSCLC). Using lung tumor models, where pemetrexed and c

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