Evolution of a Green and Sustainable Manufacturing Process for Belzutifan: Part 3─Development of a Scalable Enzymatic Oxidation Process

已完结 10 由小太阳发布于 2024/2/28 14:54:54

DOI:10.1021/acs.oprd.3c00420
文献类型：期刊论文
补充材料：只需要正文
文献链接：https://doi.org/10.1021/acs.oprd.3c00420

American Chemical Society (ACS)

Abstract：Belzutifan (MK-6482) is an FDA-approved hypoxia inducible factor 2α inhibitor for the treatment of Von Hippel–Lindau disease-associated renal cell carcinoma. One of the key synthetic steps i

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