Modular Design of Biodegradable Ionizable Lipids for Improved mRNA Delivery and Precise Cancer Metastasis Delineation In Vivo

已完结 10 由 1236544 发布于 2024/3/21 21:17:19

DOI:10.1021/jacs.3c09143
作者：Zhaoming Chen, Yang Tian, Jieyu Yang, Fapu Wu, Senyao Liu, Wenwen Cao, Weijia Xu, Tao Hu, Daniel J. Siegwart and Hu Xiong*,
文献类型：期刊论文
补充材料：只需要正文

American Chemical Society (ACS)

Abstract：Lipid nanoparticles (LNPs) represent the most clinically advanced nonviral mRNA delivery vehicles; however, the full potential of the LNP platform is greatly hampered by inadequate endosomal

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