Time-resolved cryo-EM of G-protein activation by a GPCR.

已完结 10 由 kxyf166 发布于 2024/3/20 11:06:18

DOI:10.1038/s41586-024-07153-1
作者：Makaía M Papasergi-Scott, Guillermo Pérez-Hernández, Hossein Batebi, Yang Gao, Gözde Eskici, Alpay B Seven, Ouliana Panova, Daniel Hilger, Marina Casiraghi, Feng He, Luis Maul, Peter Gmeiner, Brian K Kobilka, Peter W Hildebrand, Georgios Skiniotis
文献类型：期刊论文
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Nature

Abstract：G-protein-coupled receptors (GPCRs) activate heterotrimeric G proteins by stimulating guanine nucleotide exchange in the Gα subunit1. To visualize this mechanism, we developed a time-resolve

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