Rapid Multikilogram Scale-Up of Di- and Trifluoromethoxy Proline Derivatives

已完结 10 由小太阳发布于 2024/3/19 12:52:33

DOI:10.1021/acs.oprd.3c00493
作者：Pablo J. Cabrera, Christophe Allais, Joel T. Arcari, María González-Esguevillas, Emma L. McInturff, Matthew R. Reese
文献类型：期刊论文
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American Chemical Society (ACS)

Abstract：This report describes the synthesis, development, and scale-up (up to 10 kg) of di- and trifluoromethoxy prolines, key fragments evaluated in the development of potential antiviral SARS-CoV2

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