A Practical and Scalable Route to 6-Bromo-2,4,5-trichloropyrrolo[2,1-f][1,2,4]triazine: Process Optimization Guided by Thermal Safety Insights

已完结 20 由逍遥鬼发布于 2026/4/26 13:36:06

DOI:10.1021/acs.oprd.5c00446
文献类型：期刊论文
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文献链接：https://doi.org/10.1021/acs.oprd.5c00446

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Abstract：Herein, we report a scalable and robust route for the synthesis of 6-bromo-2,4,5-trichloropyrrolo[2,1-f][1,2,4]triazine 1. The developed process involves modification of the known method for

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