A Bispecific Monoclonal Antibody Targeting Psl and PcrV Enhances Neutrophil-Mediated Killing of Pseudomonas aeruginosa in Patients with Bronchiectasis.

已取消 10 由 zm 发布于 2024/6/19 9:39:52

DOI:10.1164/rccm.202308-1403OC
作者：Merete B Long, Amy Gilmour, Margaret Kehl, David Tabor, Ashley E Keller, Paul Warrener, Vancheswaran Gopalakrishnan, Sanna Rosengren, Megan L Crichton, Eve McIntosh, Yan Hui Giam, Holly R Keir, Wayne Brailsford, Rod Hughes, Maria G Belvisi, Bret R Sellman, Antonio DiGiandomenico, James D Chalmers
文献类型：期刊论文
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American Thoracic Society (ATS)

Abstract：Rationale: Pseudomonas aeruginosa infection is associated with worse outcomes in bronchiectasis. Impaired neutrophil antimicrobial responses contribute to bacterial persistence. Gremubamab i

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