Obesity induces PD-1 on macrophages to suppress anti-tumour immunity.

已完结 10 由 wzw 发布于 2024/6/24 15:58:39

DOI:10.1038/s41586-024-07529-3
作者：Jackie E Bader, Melissa M Wolf, Gian Luca Lupica-Tondo, Matthew Z Madden, Bradley I Reinfeld, Emily N Arner, Emma S Hathaway, KayLee K Steiner, Gabriel A Needle, Zaid Hatem, Madelyn D Landis, Eden E Faneuff, Amondrea Blackman, Elysa M Wolf, Matthew A Cottam, Xiang Ye, Madison E Bates, Kyra Smart, Wenjun Wang, Laura V Pinheiro, Anthos Christofides, DuPreez Smith, Vassiliki A Boussiotis, Scott M Haake, Kathryn E Beckermann, Kathryn E Wellen, Cynthia A Reinhart-King, C Henrique Serezani, Cheng-Han Lee, Christa Aubrey, Heidi Chen, W Kimryn Rathmell, Alyssa H Hasty, Jeffrey C Rathmell
文献类型：期刊论文
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Nature

Abstract：Obesity is a leading risk factor for progression and metastasis of many cancers1,2, yet can in some cases enhance survival3–5 and responses to immune checkpoint blockade therapies, including

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